2015

Santana P, Costa C, Cardoso G, Loureiro A, Ferrão J. (2015) Suicide in Portugal: Spatial determinants in a context of economic crisis. Health Place. 2015 Sep;35:85-94. doi: 10.1016/j.healthplace.2015.07.001. Epub 2015 Aug 14.

Mergl R, Koburger N, Heinrichs K, Székely A, Tóth MD, Coyne J, Quintão S, Arensman E, Coffey C, Maxwell M, Värnik A, van Audenhove C, McDaid D, Sarchiapone M, Schmidtke A, Genz A, Gusmão R, Hegerl U. (2015) What Are Reasons for the Large Gender Differences in the Lethality of Suicidal Acts? An Epidemiological Analysis in Four European Countries. PLoS One. 2015 Jul 6;10(7):e0129062. doi: 10.1371/journal.pone.0129062. eCollection 2015.

Boyd A, Van de Velde S, Pivette M, Ten Have M, Florescu S, O'Neill S, Caldas-de-Almeida JM, Vilagut G, Haro JM, Alonso J, Kovess-Masféty V; EU-WMH investigators. (2015) Gender differences in psychotropic use across Europe: Results from a large cross-sectional, population-based study.Eur Psychiatry. 2015 Sep;30(6):778-88. doi: 10.1016/j.eurpsy.2015.05.001. Epub 2015 Jun 4.

Tenreiro S*, Macedo D, Marijanovic Z, Outeiro TF* (2015) Analysis of protein oligomeric species by sucrose gradientes. Proteostasis: Methods and Protocols. Springer book. Editor: Rune Mattiesen. (*co-corresponding author).

Diogo LN, Pinto P, Bárbara C, Papoila AL, Monteiro EC. (2015) The Association Between Antihypertensive Medication and Blood Pressure Control in Patients with Obstructive Sleep Apnea. Adv Exp Med Biol. 2015;860:201-9. doi: 10.1007/978-3-319-18440-1_22.

Santos CA, Fonseca J, Carolino E, Lopes T, Guerreiro AS. (2015) Selenium in dysphagic patients who underwent endoscopic gastronomy for long term enteral feeding. Nutr Hosp. 2015 Dec 1;32(n06):2725-2733.

Mourão AF, Santos MJ, Melo Gomes JA, Martins FM, Mendonça SC, Oliveira Ramos F, Fernandes S, Salgado M, Guedes M, Carvalho S, Costa JA10, Brito I, Duarte C, Furtado C, Lopes A, Rodrigues A, Sequeira G, Branco JC, Fonseca JE, Canhão H. (2015) Effectiveness and long-term retention of anti-tumour necrosis factor treatment in juvenile and adult patients with juvenile idiopathic arthritis: data from Reuma.pt. Rheumatology (Oxford). 2015 Dec 15. pii: kev398. [Epub ahead of print]

Cardoso G, Graca J, Klut C, Trancas B, Papoila A. (2015) Depression and anxiety symptoms following cancer diagnosis: a cross-sectional study. Psychol Health Med. 2015 Dec 18:1-9. [Epub ahead of print]

Canhão H, Rodrigues AM, Santos MJ, Carmona-Fernandes D, Bettencourt BF, Cui J, Rocha FL, Canas Silva J, Polido-Pereira J, Pereira Silva JA, Costa JA, Araujo D, Silva C, Santos H, Duarte C, Cáliz R, Filipescu I, Pimentel-Santos F, Branco J, Sainz J, Plenge RM, Solomon DH17, Bruges-Armas J, Da Silva JA, Fonseca JE, Karlson EW. (2015) TRAF1/C5 but not PTPRC variants are potential predictors of rheumatoid arthritis response to anti-tumor necrosis factor therapy. Biomed Res Int. 2015;2015:490295. doi: 10.1155/2015/490295. Epub 2015 Mar 5.

Oliveira S, Queiroga CS, Vieira HL. (2015) Mitochondria and carbon monoxide: cytoprotection and control of cell metabolism - a role for Ca2+ ? J Physiol. doi: 10.1113/JP270955. [Epub ahead of print]

Vera-Cruz P, Rito M, Diogo L, Zagalo C, Dos Santos JM, Monteiro ME (2015) Structure of the rat tracheal mucosa after chronic intermittent hypoxia or chronic hyperbaric oxygen therapy. Histol Histopathol. 2015 Dec 9:11703. [Epub ahead of print]

Gomes P, Outeiro TF, Cavadas C (2015) Emerging Role of Sirtuin 2 in the Regulation of Mammalian Metabolism. Trends Pharmacol Sci. 2015 Nov;36(11):756-68. doi: 10.1016/j.tips.2015.08.001. Epub 2015 Nov 1.

Gaspar Â, Santos N, Piedade S, Santa-Marta C, Pires G, Sampaio G, Arêde C, Borrego LM, Morais-Almeida M (2015) One-year survey of paediatric anaphylaxis in an allergy department. Eur Ann Allergy Clin Immunol. 2015 Nov;47(6):197-205.

Diogo LN, Pinto P, Bárbara C, Papoila AL, Monteiro EC (2015) The Association Between Antihypertensive Medication and Blood Pressure Control in Patients with Obstructive Sleep Apnea. Adv Exp Med Biol. 860:201-9. doi: 10.1007/978-3-319-18440-1_22.

Mendonça MD, Caetano A, Viana-Baptista M, CHLO Headache Study Group (2015) Association of depressive symptoms with allodynia in patients with migraine: A cross-sectional study. Cephalalgia. 2015 Dec 2. pii: 0333102415620285. [Epub ahead of print]

Marinho AT, Dias CG, Pinheiro PF, Lemos AR, Antunes AM, Marques MM, Monteiro EC, Miranda JP, Pereira SA (2015) Nevirapine modulation of paraoxonase-1 in the liver: An in vitro three-model approach. Eur J Pharm Sci. 2016 Jan 20;82:147-53. doi: 10.1016/j.ejps.2015.11.019. Epub 2015 Nov 25.

Gaspar JM, Baptista FI, Macedo MP, Ambrosio AF (2015) Inside the diabetic brain: role of different players involved in cognitive decline. ACS Chem Neurosci. 2015 Dec 15. [Epub ahead of print]

Carreiro-Martins P, Papoila AL, Caires I, Azevedo S, Cano MM, Virella D, Leiria-Pinto P, Teixeira JP, Rosado-Pinto J, Annesi Maesano I, Neuparth N (2015) Effect of indoor air quality of day care centers in children with different predisposition for asthma. Pediatr Allergy Immunol. 2015 Dec 12. doi: 10.1111/pai.12521. [Epub ahead of print]

Mendes A, Papoila AL, Carreiro-Martins P, Bonassi S, Caires I, Palmeiro T, Aguiar L, Pereira C, Neves P, Mendes D, Botelho MA, Neuparth N, Teixeira JP (2015) The impact of indoor air quality and contaminants on respiratory health of older people living in long-term care residences in Porto. Age Ageing. 2015 Nov 11. pii: afv157. [Epub ahead of print]

Inácio A, Domingues NS, Nunes A, Martins PT, Moreno MJ, Estronca LM, Fernandes R, Moreno AJM, Borrego MJ, Gomes JP, Vaz WLC, Vieira OV (2015) Quaternary ammonium surfactant structure determines selective toxicity towards bacteria: mechanisms of action and clinical implications in antibacterial prophylaxis. J Antimicrob Chemother doi:10.1093/jac/dkv405

Martins FO, Delgado TC, Viegas J, Gaspar J, Scott DK, O'Doherty RM, Macedo MP,Jones JG (2015) Mechanisms by which the thiazolidinedione troglitazone protects against sucrose-induced hepatic fat accumulation and hyperinsulinemia. Br J Pharmacol. doi: 10.1111/bph.13362.

Afonso RA, Gaspar JM, Lamarão I, Lautt WW, Macedo MP (2015) Postprandial insulin action relies on meal composition and hepatic parasympathetics: dependency on glucose and amino acids: Meal, parasympathetics & insulin action. J Nutr Biochem. pii: S0955-2863(15)00224-7. doi: 10.1016/j.jnutbio.2015.08.023.

Tricò D, Baldi S, Tulipani A, Frascerra S, Macedo MP, Mari A, Ferrannini E,Natali A (2015) Mechanisms through which a small protein and lipid preload improves glucose tolerance. Diabetologia. 58(11):2503-12. doi:10.1007/s00125-015-3710-9. Epub 2015 Jul 30.

Cardoso BA, Belo H, Barata JT, Almeida AM (2015) The Bone Marrow-Mediated Protection of Myeloproliferative Neoplastic Cells to Vorinostat and Ruxolitinib Relies on the Activation of JNK and PI3K Signalling Pathways. PLoS One. 10(12):e0143897. doi: 10.1371/journal.pone.0143897. eCollection 2015.

Almeida AS, Vieira HL (2015) Assessment of mitochondrial protein glutathionylation as signaling for CO pathway. Methods Mol Biol. 1264:343-50. doi: 10.1007/978-1-4939-2257-4_30.

Ferreira-Magalhães M, Sá-Sousa A, Morais-Almeida M, Pité H, Azevedo LF, Azevedo MI, Bugalho-Almeida A, Fonseca JA (2015) Asthma-like symptoms, diagnostic tests, and asthma medication use in children and adolescents: a population-based nationwide survey. J Asthma. 1-25. [Epub ahead of print]

Pereira D, Severo M, Santos RA, Barros H, Branco J, Lucas R, Costa L, Ramos E (2015) Knee and hip radiographic osteoarthritis features: differences on pain, function and quality of life. Clin Rheumatol. [Epub ahead of print]

Ferreira-Teixeira M1, Parada B, Rodrigues-Santos P, Alves V, Ramalho JS, Caramelo F, Sousa V, Reis F, Gomes CM (2015) Functional and molecular characterization of cancer stem-like cells in bladder cancer: a potential signature for muscle-invasive tumors. Oncotarget. 6(34):36185-201. doi: 10.18632/oncotarget.5517.

Belo H, Silva G, Cardoso BA, Porto B, Minguillon J, Barbot J, Coutinho J, Casado JA, Benedito M, Saturnino H, Costa E, Bueren JA, Surralles J, Almeida A (2015) Epigenetic Alterations in Fanconi Anaemia: Role in Pathophysiology and Therapeutic Potential. PLoS One. 10(10):e0139740. doi: 10.1371/journal.pone.0139740. eCollection 2015.

Oliveira AV, Marcelo A, Rosa da Costa AM, Silva GA. (2015) Evaluation of cystamine-modified hyaluronic acid/chitosan polyplex as retinal gene vector. Mater Sci Eng C Mater Biol Appl. 2016 Jan 1;58:264-72. doi: 10.1016/j.msec.2015.08.047. Epub 2015 Aug 28.

Ladeira F, Barbosa R, Caetano A, Mendonça MD, Calado S, Viana-Baptista M (2015) Embolic stroke of unknown source (ESUS) in young patients. Int J Stroke. Suppl A100:165. doi: 10.1111/ijs.12596.

Mourão AF, Santos MJ, Mendonça S, Oliveira-Ramos F, Salgado M, Estanqueiro P, Melo-Gomes J, Martins F, Lopes A, Bettencourt BF, Bruges-Armas J, Costa J, Furtado C, Figueira R, Brito I, Branco J, Fonseca JE, Canhão H. (2015) Genetic Predictors of Poor Prognosis in Portuguese Patients with Juvenile Idiopathic Arthritis: Data from Reuma.pt. J Immunol Res. 2015:706515. doi: 10.1155/2015/706515. Epub 2015 Oct 4.

Arosio P, Carmona F, Gozzelino R, Maccarinelli F, Poli M. (2015) The importance of eukaryotic ferritins in iron handling and cytoprotection. Biochem J. 472(1):1-15. doi: 10.1042/BJ20150787.

Rapsey CM, Lim CC, Al-Hamzawi A, Alonso J, Bruffaerts R, Caldas-de-Almeida JM, Florescu S, de Girolamo G, Hu C, Kessler RC, Kovess-Masfety V, Levinson D, Medina-Mora ME, Murphy S, Ono Y, Piazza M, Posada-Villa J, Ten Have M, Wojtyniak B, Scott KM. (2015) Associations between DSM-IV mental disorders and subsequent COPD diagnosis. J Psychosom Res. ;79(5):333-9. doi: 10.1016/j.jpsychores.2015.08.005. Epub 2015 Sep 2.

Martins M, Froes F, Boavida JM, Raposo JF, Nunes B, Ribeiro RT, Macedo MP, Penha-Gonçalves C. (2015) Prevalence and impact of Diabetes mellitus (DM) among hospitalized community-acquired pneumonia (CAP) patients. European Respiratory Society. vol. 46 no. suppl 59.DOI: 10.1183/13993003.congress-2015.PA1104

Tenreiro S, Rosado-Ramos R, Gerhardt E, Favretto F, Magalhães F, Popova B, Becker S, Zweckstetter M, Braus GH, Outeiro TF. (2015) Yeast reveals similar molecular mechanisms underlying alpha- and beta-synuclein toxicity. Hum Mol Genet. 2015 Nov 18. pii: ddv470. [Epub ahead of print]

Seixas C, Choi SY, Polgar N, Umberger NL, East MP, Zuo X, Moreiras H, Ghossoub R, Benmerah A, Kahn RA, Fogelgren B, Caspary T, Lipschutz JH, Barral DC.(2015) Arl13b and the exocyst interact synergistically in ciliogenesis. Mol Biol Cell. 2015 Nov 18. pii: mbc.E15-02-0061. [Epub ahead of print]

Silva LS, Goncalves LG, Silva F, Domingues G, Maximo V, Ferreira J, Lam EW, Dias S, Felix A, Serpa J. (2015) STAT3:FOXM1 and MCT1 drive uterine cervix carcinoma fitness to a lactate-rich microenvironment. Tumour Biol. 2015 Nov 12. [Epub ahead of print]

Lopes-Coelho F, Gouveia-Fernandes S, Gonçalves LG, Nunes C, Faustino I, Silva F, Félix A, Pereira SA, Serpa J. (2015) HNF1β drives glutathione (GSH) synthesis underlying intrinsic carboplatin resistance of ovarian clear cell carcinoma (OCCC). Tumour Biol. [Epub ahead of print]

Benjet C, Bromet E, Karam EG, Kessler RC, McLaughlin KA, Ruscio AM, Shahly V, Stein DJ, Petukhova M, Hill E, Alonso J, Atwoli L, Bunting B1, Bruffaerts R, Caldas-de-Almeida JM, de Girolamo G, Florescu S, Gureje O, Huang Y, Lepine JP, Kawakami N, Kovess-Masfety V, Medina-Mora ME, Navarro-Mateu F, Piazza M, Posada-Villa J, Scott KM, Shalev A, Slade T, Ten Have M, Torres Y, Viana MC, Zarkov Z, Koenen KC (2015) The epidemiology of traumatic event exposure worldwide: results from the World Mental Health Survey Consortium. Psychol Med. 2015 Oct 29:1-17. [Epub ahead of print]

Garelli A, Heredia F, Casimiro AP, Macedo A, Nunes C, Garcez M, Dias AR, Volonte YA, Uhlmann T, Caparros E, Koyama T, Gontijo AM. 2015. Dilp8 requires the neuronal relaxin receptor Lgr3 to couple growth to developmental timing. Nat Commun. 6:8732. doi: 10.1038/ncomms9732.
PMID: 26510564

Rebelo SP, Costa R, Silva MM, Marcelino P, Brito C, Alves PM (2015) Three-dimensional co-culture of human hepatocytes and mesenchymal stem cells: improved functionality in long-term bioreactor cultures. J Tissue Eng Regen Med. 2015 Oct 29. doi: 10.1002/term.2099. [Epub ahead of print]

Thieleke-Matos C, Lopes da Silva M, Cabrita-Santos L, Portal MD, Rodrigues IP, Zuzarte-Luis V, Ramalho JS, Futter CE, Mota MM, Barral DC, Seabra MC. 2015. Host cell autophagy contributes to Plasmodium liver development. Cell Microbiol. doi: 10.1111/cmi.12524. [Epub ahead of print]

Roxo-Rosa M, Jacinto R, Sampaio P, Lopes SS (2015) The zebrafish Kupffer' s vesicle as a model system for the molecular mechanisms by which the lack of Polycystin-2 leads to stimulation of CFTR. Biol Open. 2015 Oct 2. pii: bio.014076. doi: 10.1242/bio.014076. [Epub ahead of print]

Tricò D, Baldi S, Tulipani A, Frascerra S, Macedo MP, Mari A, Ferrannini E, Natali A. 2015. Mechanisms through which a small protein and lipid preload improves glucose tolerance. Diabetologia. 58(11):2503-12.

Martins FO, Delgado TC, Viegas J, Gaspar J, Scott DK, O'Doherty RM, Macedo MP, Jones JG. 2015. Mechanisms by which the thiazolidinedione troglitazone protects against sucrose-induced hepatic fat accumulation and hyperinsulinemia. Br J Pharmacol. [Epub ahead of print]

Afonso RA, Gaspar JM, Lamarão I, Lautt WW, Macedo MP. 2015. Postprandial insulin action relies on meal composition and hepatic parasympathetics: dependency on glucose and amino acids: Meal, parasympathetics & insulin action. J Nutr Biochem. [Epub ahead of print]

Conde SV, Sacramento JF, Ribeiro MJ, Melo BF, Guarino MP. 2015. Insulin resistance: a new consequence of altered carotid body chemoreflex? Aut. Neu. 192(16)

Fernandes das Neves M, Caetano J, Oliveira S, Delgado Alves J. 2015. Immune-mediated necrotising myopathy associated with antibodies to the signal recognition particle treated with a combination of rituximab and cyclophosphamide. BMJ Case Rep

Olea E, Ribeiro MJ, Gallego-Martin T, Yubero S, Rigual R, Masa JF, Obeso A, Conde SV,Gonzalez C. 2015. The carotid body does not mediate the acute ventilatory effects of leptin. Adv. Exp. Med. Biol. 860:379-85

Oliveira S, Queiroga CS, Vieira HL. 2015. Mitochondria and carbon monoxide: cytoprotection and control of cell metabolism - a role for Ca2+? J. Physiol. [Epub ahead of print]

Pereira SA, Antunes AMM, Dias CG, Marinho AT, Harjivan SG, Fonseca M, Maia S, Branco T, Caixas U, Marques MM, Monteiro EC. 2015. Anti-histone antibodies in HIV-infected patients on Nevirapine-containing antiretroviral therapy. Clinical Therapeutics. 37(8)e142

Reichhart N, Markowski M, Ishiyama S, Wagner A, Crespo-Garcia S, Schorb T, Ramalho JS, Milenkovic VM, Fockler R, Seabra MC, Straub O. 2015. Rab27a GTPases modulates L-type Ca(2+) channel function via interaction with the II-III linker of CaV1.3 subunit. Cell Signal. 27(11):2231-40

Sacramento JF, Gonzalez C, Gonzaçez-Martin MC, Conde SV. 2015. Adenosine receptor blockade by caffeine inhibits carotid sinus nerve chemosensory activity in chronic intermittent hypoxic animals. Adv. Exp. Med. Biol. 860:133-7

Vera-Cruz P, Guerreiro F, Ribeiro MJ, Guarino MP, Conde SV. 2015. Hyperbaric oxygen therapy improves glucose homeostasis in type 2 diabetes patients: a likely involvement of the carotid bodies. Adv. Exp. Med. Biol. 860:221-5

Vitorino M, Silva AC, Inácio JM, Ramalho JS, Gur M, Fainsod A, Stenbeisser H, Belo JA. 2015. Xenopus Pkdcc1 and Pkdcc2 are two new tyrosine kinases involved in the regulation of JNK dependent Wnt/PCP signaling pathway. PloS ONE. 10(8):e0135504

Wang Y, Antunes M, Anderson AE, Kadrmas JL, Jacinto A, Galko MJ. Integrin adhesions suppress syncytium formation in the Drosophila Larval Epidermis. Curr. Biol. 25(17):2215-27

Menezes R, Tenreiro S, Macedo D, Santos CN, Outeiro TF. (2015) From the baker to the bedsode: yeast models of Parkinson's disease. Microbial Cell. 2(8). doi:10.15698/mic2015.08.219

Bugalho A, Martins C, Silva Z, Nunes G, Mendes AS, Ferreira I, Videira PA. (2015) Immature myeloid cells and tolerogenic cytokine profile in lung adenocarcinoma metastatic lymph nodes assessed by endobronchial ultrasound. Tumour Biol [Epub ahead of print]

Loureiro LR, Carrascal MA, Barbas A, Ramalho JS, Novo C, Delannoy P, Videira PA. (2015) Challenges in antibody development against Tn and Sialyl-Tn antigens. Biomolecules, 5(3):1783-809. doi: 10.3390/biom5031783

Tesi B*, Sieni E*, Neves C, Romano F, Cetica V, Cordeiro AI, Chiang S, Schlums H, Galli L, Avenali S, Tondo A, Canessa C, Henter JI, Nordenskjold M, Hsu AP, Hollan SM, Neves JF*, Azzari C*, Bryceson YT*. (2015) Hemophagocytic lymphohistiocytosis in 2 patients with underlying IFN-y receptor deficiency. J Allergy Clin Immunol, 135(6):1638-41. doi: 10.1016/j.jaci.2014.11.030.

Mendes CS, Bartos I, Márka Z, Akay T, Márka S, Mann RS. (2015) Quantification of gait parameters in freely walking rodents. BMC Biology 13:50. doi:10.1186/s12915-015-0154-0

Oliveira SR, Vieira HL, Duarte CB. (2015) Effect of Carbon Monoxide on gene expression in cerebrocortical astrocytes: validation of reference genes for quantitative Real-time PCR. Nitric Oxide. 15;49:80-9. doi: 10.1016/j.niox.2015.07.003.

Mateus, R., Lourenço, R., Fang, Y., Brito, G., Farinho, A., Valério, F. and Jacinto, A. (2015) Yap control of tissue growth relies on cell density and F-actin in zebrafish fin regeneration. Development. pii: dev.119701. [Epub ahead of print]

Ariza-Cosano, A, Bensimon-Brito, A, Gómez-Skarmeta, J L and Bessa, J (2015) sox21a directs lateral line patterning by modulating FGF signaling. Devel Neurobio, 75: 80–92. doi: 10.1002/dneu.22211

Ravasio A, Cheddadi I, Chen T, Pereira T, Ong HT, Bertocchi C, Brugues A, Jacinto A, Kabla AJ, Toyama Y, Trepat X, Gov N, Neves de Almeida L, Ladoux B. (2015) Gap geometry dictates epithelial closure efficiency. Nat Commun. 6:7683. doi: 10.1038/ncomms8683.

Duarte N, Coelho IC, Patarrão RS, Almeida JI, Penha-Gonçalves C, and Macedo MP (2015) How Inflammation Impinges on NAFLD: A Role for Kupffer Cells. BioMed Research International, vol. 2015, Article ID 984578, 11 pages, doi:10.1155/2015/984578

The importance of iron in pathophysiologic conditions, Frontiers Research Topic Ebook, Edited by: Raffaella Gozzelino and Paolo Arosio, Publisher: Frontiers Media SA, ISBN: 978-2-88919-524-4

Mauro-Lizcano M., Esteban-Martínez L., Seco E., Serrano-Puebla A., Garcia-Ledo L., Figueiredo-Pereira C., Vieira H.L.A and Boya P., (2015) New method to assess mitophagy flux by flow cytometry. Autophagy, 11(5):833-43.

Patarrão RS, Lautt WW, Macedo MP. (2015) Acute glucagon induces postprandial peripheral insulin resistance. PLoS ONE 10(5): e0127221. doi:10.1371/journal.pone.0127221